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Scientists solve the mystery of a brain “switch” that can trigger weight loss in opposite ways

Cambridge researchers have made an exciting discovery about how activating and blocking the same brain receptor can lead to weight loss. They found that the effects depend on which part of the brain is targeted, with activation reducing appetite in the brainstem and blocking promoting weight loss through the hypothalamus. This is particularly important as obesity affects over a billion people worldwide, raising risks for various diseases. These findings could pave the way for more effective obesity treatments that work better in combination.
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